Idiopathic thrombocytopenic purpura or immune thrombocytopenia also known as Immune thrombocytopenic purpura (ITP), is a type of thrombocytopenic purpura defined as an isolated low platelet count with a normal bone marrow in the absence of other causes of low platelets. Additionally, It causes a characteristic red or purple bruise-like rash and an increased tendency to bleed.[1]
Generally, Two distinct clinical syndromes manifest as an acute condition in children and a chronic condition in adults. Additionally, the acute form often follows an infection and spontaneously resolves within two months. In detail, Chronic immune thrombocytopenia persists longer than six months with a specific cause being unknown.
Furthermore, ITP is an autoimmune disease with antibodies detectable against several platelet surface structures.
Besides this, ITP is diagnosed by identifying a low platelet count on a complete blood count (a common blood test). However, since the diagnosis depends on the exclusion of other causes of a low platelet count, additional investigations (such as a bone marrow biopsy) may be necessary in some cases. [1]
If severe and of sudden onset, may cause widespread purpura, bruising, mucosal bleeding, cerebral and GI hemorrhage. Moreover, Fundal hemorrhage, persistent headache and other signs of increasing intracranial pressure suggest intracranial bleeding. In detail, Children with acute thrombocytopenia are at less risk than adults. When the condition develops after viral infection, e.g. measles, EBV infection, the duration is brief, active treatment is not required also recovery is nearly always complete.
In brief, It is most common in young adults, especially women. Most patients have purpura, epistaxis, also often menorrhagia. Symptoms tend to fluctuate, with fairly long remissions as well as periods when symptoms increase spontaneously. Commonly occur after a viral infection. Lastly, Table 25 compares features of acute ITP and chronic ITP.
Conservative treatment
Wait and see policy especially in children and young women up to the age of 25, because spontaneous remission, often permanent occurs in number of patients. Moreover, Initiate treatment when PCT <30,000
(i) Blood transfusion.
(ii) Prednisolone – 40 mg a day for 2 weeks.
Immunosuppressive therapy
Drugs such as azathioprine or cyclophosphamide are sometimes used in patients who are refractory to splenectomy and steroids or develop relapse.
Immunoglobulin preparations
Rituximab weekly in doses of 375 mg/m2 can produce remission for a period of time.
TPO receptor agonists – Romiplostim (given subcutaneously) and another orally eltrombopag (given orally) effective in raising platelet counts in patients with ITP and are recommended for adults at risk of bleeding who relapse after splenectomy or who have been unresponsive to at least one other therapy, particularly in those who have a contraindication to splenectomy. [1]
(a) Chronic cases, particularly adults, who have not had sustained response to steroids, and in whom troublesome bleeding persists after 6 months.
(b) Symptoms severe and platelet count very low.
(c) Signs of incipient central nervous system hemorrhage.
(d) Girls approaching age of onset of menstruation.
(e) Young married women likely to become pregnant.
(f) First 5 months of pregnancy.
(g) Steroid refractory
Anti-platelet auto antibodies in a pregnant woman with ITP will attack the patient’s own platelets and will also cross the placenta and react against fetal platelets. Therefore, ITP is a significant cause of fetal and neonatal immune thrombocytopenia. [1]
Homeopathy treats the person as a whole. It means that homeopathic treatment focuses on the patient as a person, as well as his pathological condition. The homeopathic medicines selected after a full individualizing examination and case-analysis.
which includes
A miasmatic tendency (predisposition/susceptibility) also often taken into account for the treatment of chronic conditions.
A homeopathy doctor tries to treat more than just the presenting symptoms. The focus is usually on what caused the disease condition? Why ‘this patient’ is sick ‘this way’?.
The disease diagnosis is important but in homeopathy, the cause of disease not just probed to the level of bacteria and viruses. Other factors like mental, emotional and physical stress that could predispose a person to illness also looked for. No a days, even modern medicine also considers a large number of diseases as psychosomatic. The correct homeopathy remedy tries to correct this disease predisposition.
The focus is not on curing the disease but to cure the person who is sick, to restore the health. If a disease pathology not very advanced, homeopathy remedies do give a hope for cure but even in incurable cases, the quality of life can greatly improved with homeopathic medicines.
The homeopathic remedies (medicines) given below indicate the therapeutic affinity but this is not a complete and definite guide to the homeopathy treatment of this condition. The symptoms listed against each homeopathic remedy may not be directly related to this disease because in homeopathy general symptoms and constitutional indications also taken into account for selecting a remedy.
Idiopathic thrombocytopenic purpura or immune thrombocytopenia also known as Immune thrombocytopenic purpura (ITP), is a type of thrombocytopenic purpura defined as an isolated low platelet count with a normal bone marrow in the absence of other causes of low platelets.
References
"*" indicates required fields
We are a multi-specialty healthcare facility, delivering world-class healthcare, at an optimum cost. Our aim is to deliver Affordable, Accessible, and Accurate healthcare to all sections of society.
