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Ebola virus

Definition

An infectious and frequently fatal disease marked by fever and severe internal bleeding, spread through contact with infected body fluids by a failover (Ebola virus), whose normal host species is unknown. [1]

Overview

  • In general, Several viruses of the family Filoviridae cause severe and frequently fatal viral hemorrhagic fevers in humans.
  • Moreover, Introduction of filoviruses into human populations is an extremely rare event that most likely occurs by either direct or indirect contact with healthy mammalian filovirus hosts or by contact with infected, sick, or deceased nonhuman primates.[1]

Sign & Symptoms

  • Fever
  • Aches and pains, e.g. severe headache and muscle and joint pain
  • Weakness also fatigue
  • Sore throat
  • Loss of appetite
  • Gastrointestinal symptoms including abdominal pain, diarrhea, also vomiting
  • Unexplained either haemorrhaging, bleeding or bruising

Causes

The family Filoviridae includes three genera: Cueva virus, Ebolavirus, also Marburg virus

These genomes contain six or seven genes that encode the following seven structural proteins:

nucleoprotein, polymerase cofactor (i.e. VP35), matrix protein (i.e. VP40), glycoprotein (e.g. GP1,2), transcriptional cofactor (VP30), secondary matrix protein (VP24), and RNA-dependent RNA polymerase (L protein). [1]

Diagnosis

Diagnosis of Ebola virus

  • Basically, Filovirus infections cannot diagnose on the basis of clinical presentation alone.
  • Acute-phase blood/serum is the preferred diagnostic specimen because it usually contains high titers of filovirions also filovirion-specific antibodies.
  • Consequently, diagnostic samples should collect with great caution and with use of proper personal protective equipment and strict barrier nursing techniques.
  • In detail, With adherence to established bio safety precautionary measures, samples should sent in suitable transport media to national or international WHO reference laboratories.
  • All in all, Direct IgM and IgG or IgM capture ELISA use for the detection of filovirion-targeting antibodies from patients in later stages of disease [1]

Treatment

Treatment of Ebola virus

  • Any treatment of patients with suspected or confirmed filovirus infection must be administered under increased safety precautions by experienced specialists using appropriate personal protective equipment .
  • Postexposure vaccination with filovirus GP1,2.
  • Expressing recombinant replicating vesicular stomatitis Indiana virus; administration of specific filovirus genome- or transcript-targeting small interfering RNAs or phosphorodiamidate morpholino oligomers.
  • Administration of filovirus specific antibodies or antibody cocktails ; and use of a synthetic adenosine analog  that acts as a non-obligate RNA chain terminator.
  • In the absence of these candidate treatments, measures to stabilize patients include those generally recommended for severe septicemia/sepsis/shock.
  • Pain management and administration of antipyretics and antiemetic should always be considered. [1]

Complications

Complications of Ebola virus

Given the severe immunosuppression induced by filovirus infection, secondary infections should be kept in mind and appropriately treated as early as possible.

Pregnancy and labour cause severe and frequently fatal complications in filovirus infections due to clotting factor consumption, fetal loss, and/or severe blood loss during birth. [1]

Homoeopathic Treatment

Homoeopathic Treatment of Ebola virus

Homeopathy treats the person as a whole. It means that homeopathic treatment focuses on the patient as a person, as well as his pathological condition. The homeopathic medicines are selected after a full individualizing examination and case-analysis, which includes the medical history of the patient, physical and mental constitution, family history, presenting symptoms, underlying pathology, possible causative factors etc.

What Homeopathic Doctors do?

A miasmatic tendency (predisposition/susceptibility) is also often taken into account for the treatment of chronic conditions. A homeopathy doctor tries to treat more than just the presenting symptoms. The focus is usually on what caused the disease condition? Why ‘this patient’ is sick ‘this way’.

The disease diagnosis is important but in homeopathy, the cause of disease is not just probed to the level of bacteria and viruses. Other factors like mental, emotional and physical stress that could predispose a person to illness are also looked for. No a days, even modern medicine also considers a large number of diseases as psychosomatic. The correct homeopathy remedy tries to correct this disease predisposition.

The focus is not on curing the disease but to cure the person who is sick, to restore the health. If a disease pathology is not very advanced, homeopathy remedies do give a hope for cure but even in incurable cases, the quality of life can be greatly improved with homeopathic medicines.

The homeopathic remedies

The homeopathic remedies (medicines) given below indicate the therapeutic affinity but this is not a complete and definite guide to the homeopathy treatment of this condition. The symptoms listed against each homeopathic remedy may not be directly related to this disease because in homeopathy general symptoms and constitutional indications are also taken into account for selecting a remedy.

Medicines of Ebola virus:

Crotalus horridus:

  • Specifically in Bilious fever with yellow face, gnawing, aching pain in liver, bloody evacuation, right lung hepatized, dry tongue, urine dark, unconsciousness, cold clammy perspiration.
  •  All fevers which present a either hemorrhagic or putrescent character, with epistaxis, extreme prostration and induration of tonsils.

Arsenicum album:

  • High temperature. Periodicity marked with adynamic, Septic fevers.
  • Paroxysms incomplete, with marked exhaustion, Hay fever.
  • Cold sweats. Additionally, Typhoid, not too early, Complete exhaustion.
  • Besides this, Delirium; worse after midnight. Great restlessness. Great heat especially, about 3 a.m. Sordes.

Lachesis:

  • Chilly in back; feet icy cold; hot flushes also hot perspiration.
  • Paroxysm returns after acids. Intermittent fever especially in every spring.

Millefolium:

  • Especially indicated in Ebola virus infection.
  • Intermittent fever: quartan; tertian; irregular. Furthermore, Scarlet fever epidemic, with excessive angina and violent fever.
  • Chilliness with pains in left kidney. Exanthema of difficult development and delirium. Hectic fever with hemoptysis.
  • Colliquative sweats. Fever heat with thirst.
  • Phosphorus: Chilly every evening. Cold knees at night. Adynamic with lack of thirst, but unnatural hunger.
  • Hectic, with small, quick pulse; viscid night- sweats. Stupid delirium. Lastly, Profuse perspiration.

Baptisia:

  • Chill, with rheumatic pains and soreness all over body. Heat all over, with occasional chills.
  • Chill about 11 a.m. Adynamic fever, Typhus fever. Shipboard fever.[2]

Diet & Regimen

  • Avoid cold drinks /cold food
  • Eat fresh food
  • Maintain cleanliness
  • Drink Hurble tea
  • Respiratory exercise

FAQs

Frequently Asked Questions

What is Ebola virus?

An infectious and frequently fatal disease marked by fever and severe internal bleeding, spread through contact with infected body fluids by a failover (Ebola virus), whose normal host species is unknown.

Homeopathic Medicines used by Homeopathic Doctors in treatment of Ebola virus?

  • Crotalus horridus
  • Arsenicum album
  • Lachesis
  • Millefolium
  • Baptisia

What causes Ebola virus?

Cueva virus, Ebolavirus, and Marburg virus

What are the symptoms of Ebola virus?

  • Fever
  • Aches also pains
  • Weakness and fatigue
  • Sore throat
  • Loss of appetite
  • Abdominal pain, diarrhea, also vomiting
  • Unexplained hemorrhaging, bleeding or bruising

References:

  1. [1] Harrison-s_Principles_of_Internal_Medicine-_19th_Edition-_2_Volume_Set
  2. [2] Materia Medica By Boericke W.